(+/-)-alpha-Lipoamide
- Name (+/-)-alpha-Lipoamide
- CAS 940-69-2
- Purity 99%
Product Details
Quality products?make an important contribution to long-term revenue and profitability. Cost-effective customized wholesale (+/-)-alpha-Lipoamide 940-69-2
1.What is the (+/-)-alpha-Lipoamide ?
(±)-α-Lipoamide may be used in treatment of insulin resistance by stimulating mitochondrial biogenesis. When used in combination with Alprostadil, it has shown to have a good therapeutic effect on early diabetic nephropathy.
-
-
40846-94-4
thioctic acid-N-hydroxysuccinimide ester
-
-
940-69-2,165171-77-7,3206-73-3
lipoamide
| Conditions | Yield |
|---|---|
|
With
ammonium hydroxide;
In
dichloromethane; acetonitrile;
at 20 ℃;
for 1h;
Inert atmosphere;
|
93%
|
-
-
1077-28-7,62-46-4
Thioctic acid
-
-
940-69-2,165171-77-7,3206-73-3
lipoamide
| Conditions | Yield |
|---|---|
|
With
ammonium hydroxide; immobilized Candida antarctica Lipase B;
In
1,4-dioxane; water;
at 50 ℃;
for 72h;
Reagent/catalyst;
Sealed tube;
Enzymatic reaction;
|
34%
|
|
With
tetrahydrofuran; triethylamine; isobutyl chloroformate;
Behandeln der Reaktionsloesung mit Ammoniak enthaltendem Tetrahydrofuran;
|
|
|
Multi-step reaction
with
2
steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C / Inert atmosphere
2: ammonium hydroxide / dichloromethane; acetonitrile / 1 h / 20 °C / Inert atmosphere
With
ammonium hydroxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane; acetonitrile;
|
|
|
With
ammonium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
|
2.What is the CAS number for (+/-)-alpha-Lipoamide ?
The CAS number of (+/-)-alpha-Lipoamide is 940-69-2.
More information of (+/-)-alpha-Lipoamide 940-69-2 are:
|
CAS?Number |
940-69-2 |
|
Density |
1.169 g/cm3 |
|
Melting Point |
127-129 °C(lit.) |
|
Boiling Point |
399.2 °C at 760 mmHg |
|
Flash Point |
195.2 °C |
|
Vapor Pressure |
1.39E-06mmHg at 25°C |
|
Refractive Index |
1.5364 (estimate) |
|
HS CODE |
2934999090 |
|
PSA |
93.69000 |
|
LogP |
2.88610 |
|
Pka |
16.59±0.40(Predicted) |
3.What are another words for (+/-)-alpha-Lipoamide ?
Synonyms?for?(+/-)-alpha-Lipoamide 940-69-2:1,2-Dithiolane-3-valeramide(8CI); a-Lipamide (6CI); (?à)-1,2-Dithiolane-3-pentanamide; (?à)-1,2-Dithiolane-3-valeramide; (?à)-Thioctic acid amide;5-(1,2-Dithiolan-3-yl)pentanamide; 5-(1,2-Dithiolan-3-yl)valeramide;DL-6,8-Thioctamide; DL-Lipoamide; DL-a-Lipoic acid amide; Lipamide; Lipoacin; Lipoamid;Lipoamide; Lipoicin; NSC 90787; Pathoclon; Thioami; Thioctamid; Thioctamide;Thioctic acid amide; Thioctic amide; Thiotomin; Ticolin; Vitamin N; a-Lipoamide
4.What is the molecular formula of (+/-)-alpha-Lipoamide?
The chemical formula of ?(+/-)-alpha-Lipoamide is?C8H15 N O S2 which containing 8 Carbon atoms,15 Hydrogen atoms,1 Nitrogen atoms,1 Oxygen atoms and 2 Sulfur atoms,and the molecular weight of??(+/-)-alpha-Lipoamide?is 205.345.
5.What is (+/-)-alpha-Lipoamide (940-69-2) used for?
(+/-)-alpha-Lipoamide, also known as lipoamide, is a monocarboxylic acid amide that results from the formal condensation of the carboxy group of lipoic acid with ammonia. It plays a crucial role in various biological processes and has potential therapeutic applications.
Used in Pharmaceutical Industry:
(+/-)-alpha-Lipoamide is used as a therapeutic agent for the treatment of insulin resistance by stimulating mitochondrial biogenesis. This helps improve insulin sensitivity and glucose metabolism in individuals with insulin resistance.
Used in Diabetic Nephropathy Treatment:
In combination with Alprostadil, (+/-)-alpha-Lipoamide has shown good therapeutic effects on early diabetic nephropathy. This combination therapy may help slow down the progression of kidney damage in diabetic patients and improve their overall health.
InChI:InChI=1/C8H15NOS2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H2,9,10)/t7-/m1/s1
Relevant articles related to (+/-)-alpha-Lipoamide:
|
Article |
Source |
|
Lipase-catalyzed amidation of carboxylic acid and amines |
Manova, Daniela,Gallier, Florian,Tak-Tak, Lotfi,Yotava, Lyubov,Lubin-Germain, Nadège supporting information, p. 2086 - 2090 (2018/05/04) |
|
Redox cycling of β-lapachone and related o-naphthoquinones in the presence of dihydrolipoamide and oxygen |
Molina Portela, Maria P.,Stoppani, Andres O.M. , p. 275 - 283 (2007/10/03) |
6.Buy (+/-)-alpha-Lipoamide with the best price .
Airsea(Taizhou) Pharmaceutical Limited is a quality supplier of (+/-)-alpha-Lipoamide. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on (+/-)-alpha-Lipoamide 940-69-2.
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