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1,7-DIMETHYLXANTHINE

  • Name 1,7-DIMETHYLXANTHINE
  • CAS 611-59-6
  • Purity 99%
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What is the 1,7-DIMETHYLXANTHINE ?

1,7-DIMETHYLXANTHINE is off-white to pale yellow solid, while it's Molecular Formula is C7H8N4O2. Paraxanthine is an adenosine receptor ligand and a major metabolite of caffeine.1,7-DIMETHYLXANTHINE is a contaminant of emerging concern (CECs).

What is the CAS number for 1,7-DIMETHYLXANTHINE ?

The CAS number of 1,7-DIMETHYLXANTHINE is 611-59-6.

More information of 1,7-DIMETHYLXANTHINE 611-59-6 are:

Synonyms

Paraxanthine(6CI,7CI,8CI);1,7-Dimethylxanthine;NSC 400018;1H-Purine-2,6-dione,3,7-dihydro-1,7-dimethyl-;

CAS?Number

611-59-6

Molecular Formula

C7H8N4O2

Molecular Weight

180.166

Density

1.6 g/cm3

Melting Point

294-296 °C(lit.)

Boiling Point

312.97°C (rough estimate)

Flash Point

9℃

PSA

72.68000

LogP

-1.03970

Pka

pKa 8.5 (Uncertain)

What is 1,7-DIMETHYLXANTHINE (611-59-6) used for?

Paraxanthine is an inhibitor of phosphodiesterase 9 (PDE9) and an antagonist of adenosine receptors A1 and A2 (Kis = 35 and 22 μM, respectively in equine forebrain tissues). It is the main metabolite of caffeine in humans, making up 80% of the three dimethylxanthine metabolites produced by caffeine demethylation. Paraxanthine increases locomotor activity and counteracts adenosine receptor agonist-induced motor depression in rats not habituated to caffeine. At a dose of 30 mg/kg, paraxanthine induces a significant increase in striatal cGMP and extracellular striatal dopamine concentrations in vivo. It also promotes wakefulness and increases locomotor activity and core temperature in narcoleptic transgenic mice without increasing behavioral anxiety.

InChI:InChI=1/C7H8N4O2/c1-10-3-8-5-4(10)6(12)11(2)7(13)9-5/h3H,1-2H3,(H,9,13)

Articles related to 1,7-DIMETHYLXANTHINE:

Article

Source

Preparation method of paraxanthine

-

, (2021/06/22)

Preparation methods of 1, 7-dimethylxanthine and intermediate thereof, and intermediate

-

, (2019/04/04)

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