CERULENIN

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1.What is the CERULENIN ?

Cerulenin is used as an antifungal antibiotic that inhibits sterol and fatty acids biosynthesis. Cerulenin induces apoptosis in tumor cell lines. It can be a useful biochemical tool with applications for the study of metabolism and function of fatty acids in the bacterial cell membrane and in yeast. An extensive review including the properties, uses, mechanism of action and structure has been reported.

2.What is the CAS number for CERULENIN ?

The CAS number of CERULENIN is 17397-89-6.

More information of CERULENIN 17397-89-6 are:

3.What are another words for CERULENIN ?

Synonyms?for?CERULENIN 17397-89-6:7,10-Dodecadienamide,2,3-epoxy-4-oxo- (8CI);Oxiranecarboxamide, 3-(1-oxo-4,7-nonadienyl)-, [2R-[2a,3a(4E,7E)]]-;Oxiranecarboxamide,3-[(4E,7E)-1-oxo-4,7-nonadienyl]-, (2R,3S)- (9CI);(+)-Cerulenin;Helicocerin;

4.What is the molecular formula of CERULENIN?

The chemical formula of ?CERULENIN is?C₁₂ H₁₇ NO₃ which containing 12 Carbon atoms,17 Hydrogen atoms,1 Nitrogen atoms and 3 Oxygen atoms,and the molecular weight of??CERULENIN?is 223.272.

5.What is CERULENIN (17397-89-6) used for?

Cerulenin is a fungal metabolite originally isolated from C. caerulens that has diverse biological activities. It is active against a variety of bacteria, including B. subtilis, E. coli, B. megaterium, and B. anthracis (MICs = 12.5, 12.5, 50, and 50 μg/ml, respectively) and fungi, including strains of C. albicans, T. rubrum, and A. fumigatus (MICs = 0.8-3.7, 3.1-6.2 and 12.5-50 μg/ml, respectively). Cerulenin is an inhibitor of fatty acid synthase type I (FAS-I) and FAS-II (IC50s = 3 and 20 μM, respectively, for the E. coli enzymes). It inhibits fatty acid synthesis in a panel of human cancer cell lines, including breast, ovarian, and endometrial cancer cells, as well as reduces tumor growth in a OVCAR-3 mouse xenograft model.

InChI:InChI=1/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)/b3-2+,6-5+

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6.Buy CERULENIN with the best price .

Airsea(Taizhou) Pharmaceutical Limited is a quality supplier of CERULENIN. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on CERULENIN 17397-89-6.